For the first time this season, two 49ers offensive starters are listed as questionable for an upcoming game -- left tackle Joe Staley (concussion) and receiver Mario Manningham (concussion). For the third straight week, running back Brandon Jacobs (knee) also is listed as questionable despite having practiced in full for three straight weeks.
Manningham wore a black, "no contact" jersey in practice this week to protect his shoulder. But he spoke like someone who expected to play against the physical Seahawks. As a member of the Giants, he played against Seattle each of the past two seasons, and he knows the Seahawks cornerbacks will be in the 49ers receivers' faces this evening.
"I like when teams press me," he said. "It feels like it gives me the advantage."
Does he feel like cornerbacks are challenging him when he does it?
"I like to step up to the challenge," Manningham said. "I like to go out there and try to make plays. If they're going to press me -- bring it on."
As for Staley, his status likely won't be known until 90 minutes before kickoff when teams submit their inactive lists. Whether he plays or not, left tackle will be a focal point tonight. Seahawks speed rusher Chris Clemons (team-leading seven sacks) will line up opposite the left tackle and the Seahawks also will place rookie Bruce Irvin, whom the 49ers were eying before the draft, on that side of the line at times.Â
Probable: K David Akers (illness), QB Alex Smith (finger), P Andy Lee (thumb), LB Tavares Gooden (elbow)
One of Seattle's strengths is their young safeties. Strong safety Kam Chancellor, who is tied for the team lead with linebacker K.J. Wright in tackles, will play with an ankle injury.
Out: G John Moffitt (knee)
Doubtful: CB Byron Maxwell (hamstring)
Probable: S Kam Chancellor (ankle), DT Clinton McDonald (groin)
-- Matt Barrows