Brandon Jacobs once again is a healthy scratch for the 49ers, who are not messing with their recent formula for rushing success despite Frank Gore's sore ribs. Left tackle Joe Staley also will start despite dealing with pneumonia, according to CSN Bay Area, and missing practice last week. Gore did not miss a practice after suffering bruised ribs Oct. 18.
Jacobs was in uniform Oct. 18 against Seattle but was the only 49er who didn't get into the game. "I'm ready whenever coach calls my name," Jacobs told The Bee last week. "I can't do anything about what's going on, but I can work hard and show coach that I'm ready, that I'm healthy."
Otherwise, the 49ers inactives are the same as they've been for weeks: Jacobs, quarterback Scott Tolzien, receiver A.J. Jenkins, running back LaMichael James, safety Trenton Robinson, guard Joe Looney and nose tackle Ian Williams.
Meanwhile, ex-49ers offensive lineman Adam Snyder (quad) is inactive for the Cardinals. Rich Ohrnberger will start at right guard in his place. This will be Ohrnberger's first start. He's played in 12 games in his career, none since 2010.
The other 49ers inactives are quarterback Kevin Kolb, receiver LaRon Byrd, cornerback Greg Toler, linebacker Jamaal Westerman, guard Senio Kelemete and tight end Todd Heap.
At about 4:10 local time, the roof was opened at University of Phoenix Stadium. They're playing this one under the stars.
-- Matt Barrows