One 49ers starter, Ray McDonald, has been ruled out for Sunday's game against the Saints, but two others are on track to play.
Tight end Vernon Davis and safety Eric Reid officially are listed as questionable on the injury report after suffering concussions on Sunday against the Panthers. Both practiced throughout the week and on Friday went through the final step - a simulated impact drill - of the league's post-concussion protocol.
If they are asymptomatic on Saturday, both will play in New Orleans. "Pretty much the same as last time," reported Reid, who suffered a concussion in Week 2 but was healthy enough to play in Week 3. Reid and Davis actually went against each other to administer to the contact needed for the final test.
"Just had to get banged around a little bit," Davis said. "And that's pretty much it for now. Now it depends on how I feel the next couple of days." Both players have said they've felt fine during the week.
McDonald, meanwhile, suffered a high-ankle sprain in the second quarter against the Panthers. Tony Jerod-Eddie and Demarcus Dobbs filled in for him in the second half, and they will be tapped to do so again against the Saints. Neither has started an NFL game.
Third tight end Garrett Celek missed practice this week with a hamstring injury and is listed as doubtful. The 49ers have an open roster spot and could promote practice-squad player Derek Carrier to the 53-man squad. Jim Harbaugh, however, said no decision has been made yet on whether to elevate Carrier.
Harbaugh indicated that Michael Crabtree, who spent most of the week practicing and going through rehabilitation on his own, would not play against the Saints. The 49ers have a week and a half to add Crabtree to the 53-man roster. Even at that point, however, it may be that he continues to work his way back from his Achilles' injury before playing in a game.
Harbaugh also confirmed that rookie running back Marcus Lattimore would join the team for practice next week. Lattimore can do so for 21 days. However, Harbaugh reiterated that there is no plan to bring the rookie onto the 53-man roster this year.
Out: DE Ray McDonald (ankle), WR Quinton Patton (foot)
Doubtful: TE Garrett Celek (hamstring)
Questionable: TE Vernon Davis (concussion), WR Mario Manningham (knee), RB Bruce Miller (hamstring), S Eric Reid (concussion), LB Dan Skuta (foot)
Probable: CB Tarell Brown (knee), DT Quinton Dial (ankle), RB Frank Gore (ankle), G Mike Iupati (knee), P Andy Lee (neck), DT Justin Smith (shoulder)
Out: S Kenny Vaccaro (concussion), TE Benjamin Watson (concussion)
Probable: TE Jimmy Graham (elbow, foot), S Roman Harper (knee), DE Akiem Hicks (back), S Malcolm Jenkins (knee), DE Cameron Jordan (ankle), LB Curtis Lofton (hamstring, ankle), DT Tyrunn Walker (knee)
-- Matt Barrows