She becomes the sixth of California's 53 incumbents to announce they are leaving Congress after this year.
Negrete McLeod, who served a dozen years in the California Legislature before defeating then-Rep. Joe Baca in the redrawn 35th Congressional District in 2012, said she decided to leave Congress because "my desire to represent this community locally, where I have lived for more than forty years, and where I have long served as an elected official, won out.
"My federal, state, and local experience will allow me the opportunity to effectively represent the constituents of the Fourth District," Negrete McLeod, 72, added in a statement.
State Sen. Norma Torres, D-Pomona, has been mentioned as a likely candidate for the 35th. She was elected to the Senate in a May 2013 special election to serve out the remainder of Negrete McLeod's Senate term.
35th Congressional District
Torres was not immediately available for comment. She has filed a statement of intent to run for re-election in the redrawn 20th Senate District.
In an interview, Baca all but ruled out another campaign in the 35th. He is running in the adjoining 31st.
"Things look good for me in the 31st. I'm staying there," Baca said, but added, "If you can convince me otherwise who knows. I'm not going to rule anything out."
Negrete McLeod becomes the second member of Congress from San Bernardino County to announce in recent days days that they won't seek re-election. Rep. Gary Miller, R-Rancho Cucamonga, announced his retirement last week in the 31st Congressional District.
Unlike Miller, whose re-election prospects were much in doubt, Negrete McLeod represents a safely Democratic seat and had no announced opposition for re-election.
Negrete McLeod has almost $900,000 on hand for a supervisorial campaign. Among her opponents is Assemblyman Curt Hagman, R-Chino Hill.
PHOTO: State Sen. Gloria Negrete McLeod, D-Chino, speaks in the state Senate in June 2012. Associated Press/Rich Pedroncelli