Last year Burbank won a tight 14-7 decision at Napa on two long touchdown runs by Calvin Green to open the season.
That win set the stage for the best run in Titans' history.
They reeled off 11 more wins before losing to Oak Ridge in the Sac-Joaquin Section Division I semfinals.
No. 8 Burbank is hoping Friday's 35-9 win over visiting Napa might spark another long run.
This time they didn't need a big game from Green, though the multi-talented star still excelled.
Green, who has verbally committed to Washington State, opened the game on the first play from scrimmage by going off tackle and rambling 70 yards down the right sideline for an apparent touchdown. It was called back on a penalty.
Green, who rushed for 1,178 yards and 12 touchdowns last season, finished with 31 yards on six carries and caught two passes for 23 yards.
But the Titans are loaded again this season, even if the roster is smaller at 31 players.
With Sacramento State verbal recruit Printess Johnson leading the way at tackle, senior quarterback Ernest Jenkins and junior running back Harrison Anderson each rushed for two touchdowns and Ben Jones added a fifth on a 37-yard run.
"We didn't need Calvin Green to do it all tonight," said Burbank coach John Heffernan. "It was a good team effort. We played well."
Jenkins finished with 164 yards rushing on 20 carries; and Anderson, the quarterback on last year's JV team, added 66 on four carries, including a 57-yard touchdown.
On defense, despite being double teamed much of the night, defensive tackle and national recruit Ngalu Tapa dominated along the front line and in the Indians' backfield along with sophomore brother Leki Tapa. Ngalu Tapa and Gerald Pliman each had two sacks.
The Titans also recovered three fumbles, including one by Green.
But it also was a sloppy first game that took three hours to play.
Officials called 27 penalties for 265 yards and the Titans had three touchdowns called back.
The game also was delayed 15 minutes late in the fourth quarter after Napa's Kiel Brown suffered a chest injury and had to be taken by stretcher off the field for precautionary reasons.
Burbank's win sets up a big game on Friday against No. 5 Pleasant Grove at Sheldon.
Heffernan and Pleasant Grove's Joe Cattolico are close friends and have tried to avoid playing each other for years.
In other games:
No. 1 Folsom 56, Woodcreek 21 at Folsom - Jake Browning completed 31 of 38 passes for 438 yards and seven touchdowns a year after tossing 10 touchdowns as the Bulldogs rolled the Timberwolves. Cole Thompson had 131 yards receiving and a touchdown, and Troy Knox caught two touchdown passes. Baily Laolagi ran for a score and caught a touchdown from Browning, who leads his team against No. 2 Granite Bay next Friday. Granite Bay did not play Friday.
No. 3 Elk Grove 27, Lincoln-Stockton 0 at Elk Grove - Wadus Parker rushed for 218 yards on 32 carries and three touchdowns and Tommy Arnold hit tight end Noah Letuligasenoa for a 49-yard touchdown for the Thundering Herd. Spencer Sheff rushed for 71 yards for Elk Grove.
No. 4 Del Oro 27, Logan-Union City 14 in Loomis - Te'Von Rhyne scored two touchdowns and Dylan Kainrath added one as the Golden Eagles beat the Bay Area power in the Honor Bowl. The Colts scored first, but on a screen pass from quarterback Michael Moore, Rhyne came out of a pile of defenders at midfield and ran 51 yards for a score, the start of a 27-0 run.
No. 7 Oak Ridge 38, No. 10 Vista del Lago 0 in El Dorado Hills - Ian Book threw three touchdown passes, including 81 and eight-yard scoring strikes to Justin Priest as the Trojans rolled the Eagles.
No. 9 Grant 33, Paradise 14 at Paradise - Donovan Brown threw four touchdown passes, three to Ariyon Huff, and the defense forced six turnovers for the Pacers. Grant trailed 14-0 in the first quarter.
Roseville 23, No. 11 Cosumnes Oaks 7 in Roseville - Matt Razzano returned an interception 65 yards, Kyle Downie ran 20 yards for a score and threw a 20-yard touchdown pass to Gabe Lira and Max Fereira booted a 47-yard field goal as the Tigers beat the Wolfpack.
No. 12 Inderkum 46, Monterey Trail 12 at Monterey Trail - Terrence White and Marcus Gilbert each ran for two touchdowns and Larry Hardy caught a 26-yard touchdown pass from C.J. Spencer as the Tigers rolled past the Mustangs.
Central Catholic 49, No. 17 Placer 13 in Auburn - Matt Ringer rushed for 181 yards and four touchdowns and also had a 45-yard halfback option touchdown in the Raiders' win over the Hilmen. Cameron Scott led Placer with 118 rushing yards, including a 71-yard touchdown.
No. 18 Center 70, Encina 0 in Antelope - Joe Swen rushed for 164 yards and four touchdowns on 10 carries and also caught a three-yard touchdown pass from Tyrel Anderson as the Cougars defeated the Bulldogs.
Capital Christian 48, Golden Sierra 0 in Garden Valley - Justice Shelton-Mosley accounted for 388 total yards and scored five touchdowns for the Cougars, coming off a school-record 10-2 season. The junior fly back also had an interception and forced a fumble.
Sheldon 52, McNair 14 at Sheldon - Nolan Merker accounted for four touchdowns, including a 51-yard touchdown strike to Taron Johnson on the first offensive play for the Huskies, and later for a 25-yard strike. Josiah Cammack had a 35-yard touchdown for Sheldon.
Colfax 28, Argonaut 20 in Colfax - Michael Wilson completed 18 of 29 passes for 251 yards and three touchdowns, including two of 16 and 26 yards to Chas Reisinger, as the Falcons defeated the Mustangs from Jackson. Reisinger finished with six catches for 96 yards.
Whitney 21, Vintage 14 in Rocklin - Drew Romo completed 13 of 24 passes for 171 yards and three touchdowns including two to Kwane Wilkinson in the Wildcats win over the Crushers. Wilkinson also rushed for 156 yards on 21 carries.
Rosemont 37, Cordova 7 in Rancho Cordova - Eddie Ortiz rushed for 181 yards and a touchdown on 18 carries, had 10 tackles and forced four fumbles in the Wolverines win over the Lancers.
Christian Brothers 41, River City 10 at Hughes Stadium - Mason Stahley ran for a 70-yard touchdown, returned a punt 45 yards for a score and caught a 10-yard touchdown pass from Chris Guillen. Guillen also threw touchdown passes of 79 and 40 yards to Erik Bloomquist.
Woodland 24, Bella Vista 21 in Woodland - Joseph Duran rushed for 102 yards and two touchdowns and Devin Jones intercepted a pass in the end zone with 34 seconds left to lift the Wolves over the Broncos. Austin Harmer was 14 of 24 for 245 yards and a touchdown for Bella Vista.
River Valley 48, Central Valley 17 in Shasta Lake - T.J. Dove rushed for 279 yards on 28 carries and scored three touchdowns and Devin Cates was 8 for 13 for 117 yards and three touchdowns in the Falcons win over their Northern Section opponent.
Yuba City 40, Davis 0 in Yuba City - Austin Thompson caught a 72-yard touchdown pass from Isaac Lessard, Omar Herrera rushed for 97 yards and two touchdowns on seven carries and the Honkers defense held the Blue Devils to 119 total yards in the one-sided win.
Call The Bee's Bill Paterson (916) 326-5506. The Bee's Joe Davidson and correspondent Trevor Horn contributed to this report.